Targeted Chlorine e6 based Photodynamic Therapy for Nasal Cancer–A single case report

Case report: In this case study we report the treatment outcome of using photodynamic diagnosis (PDD) and chlorine e6 based PDT as part of adjuvant therapy in a patient with locally advanced nasal carcinoma. The patient had previously refused surgical ablation of the nose for cosmetic and psychological reasons. Chlorin E6 was given IV at a dose of 1 mg/sqm BSA three hours before PDT procedure. PDD was performed with blue light (405 nm) prior to PDT with red light laser (670 nm). PDT effect is based on a defi ned local photodiagnostic measurements of chlorine E6. The multi-modal approach resulted in local tumor control with an acceptable cosmetic outcome.